Sodium Hydroxide → HCID 14347297, compound

Participants

Reaction Steps

As described in Example 99, (E,E)-5-(4-methoxyphenyl)-2,4-heptadecadienoic acid methyl ester (11.9 g) was saponified in a refluxing mixture of methanol (30 mL) and 2N NaOH (30 mL). After 2.5 hours the crude acid was isolated in the usual way and was crystallized from hexane to give 7.86 g of (E,E)-5-(4-methoxyphenyl)-2,4-heptadecadienoic acid. A sample was recrystallized from the same solvent to afford the analytical specimen, mp 85°-88° C.

Provenance & Evidence