4-Nitrophenol → HCID 14347438, compound

Participants

Reaction Steps

As in Example 115, (E)-5,5-bis(2-methoxyphenyl)-2,4-pentadienoic acid (5 g) and 4-nitrophenol (2.7 g) in dichloromethane (35 mL) was treated with 1,3-dicyclohexylcarbodiimide (3.34 g). The mixture was stirred at 0°-5° C. for 30 minutes and then at room temperature for 18 hours. After the usual work up, the crude product was crystallized from 2-propanol to give 6.1 g of (E)-5,5-bis(2-methoxyphenyl)-2,4-pentadienoic acid 4-nitrophenyl ester, mp 141.5°-143° C. A portion from the 2-propanol to yield the analytical sample, mp 142°-143° C.

Provenance & Evidence