4-Nitrophenol → HCID 14347451, compound

Participants

Reaction Steps

As in Example 115, (2E,4Z)-5-(4-methoxyphenyl)-5-(3-pyridinyl) -2,4-pentadienoic acid (5.7q) and 4-nitrophenol (306 g) in 80 mL of dichloromethane was treated with 1,3-dicyclohexylcarbodiimide (4.2 g) and the mixture was stirred at room temperature for 18 hours. After the usual work up, the ester was crystallized from 2-propanol to give 7.3 g of (E,E)-5-(4-methoxyphenyl)-5-(3-pyridinyl)-2,4-pentadienoic acid 4-nitrophenyl ester 129.5°-131° C. The analytical specimen was obtained from the same solvent, mp 130°-131° C.

Provenance & Evidence