HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-(4-Chloro-3-(trifluoromethyl)phenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 4-Bromo-2-chloro-alpha,alpha,alpha-trifluorotoluene | HCID 67959 | — |
| Product | 1-(4-Chloro-3-(trifluoromethyl)phenyl)piperazine | HCID 2778137 | 78.2% |
Reaction Steps
Beginning with 5-bromo-2-chlorobenzotrifluoride (602 mg) and piperazine (1 g), 480 mg of the title compound was recovered by the procedure described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE041315E1 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-f9aec33f77d543dca7f6a8dc6e47c7b7 |
| Source note | uspto-grants-2010_05 |