Boron tribromide → HCID 68678485, compound

Participants

Reaction Steps

A solution of 32 mg of the product of Step B and 251 mg of boron tribromide in dichloroethane (2.0 mL) was heated in a sealed tube at 125° C. After two h, the reaction was cooled to ambient temperature and the excess reagent carefully quenched by the addition of water. The resulting mixture was extracted with EtOAc and the organic layer washed with sat. sodium chloride, dried over sodium sulfate, filtered, and concentrated. The residue was purified by silica gel chromatography to afford the title compound as a tan solid. MS (M+H+)=417.4.

Provenance & Evidence