1-(2-Methoxyethyl)piperazine → HCID 68489961, compound

HRID 2233154Notes

Reaction equation

HRID 2233154 reaction equation
[C:1]([C:5]1[O:6][C:7]2[C:13]([S:14](Cl)(=[O:16])=[O:15])=[C:12]([Cl:18])[CH:11]=[CH:10][C:8]=2[N:9]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:19][O:20][CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[C:1]([C:5]1[O:6][C:7]2[C:13]([S:14]([N:26]3[CH2:27][CH2:28][N:23]([CH2:22][CH2:21][O:20][CH3:19])[CH2:24][CH2:25]3)(=[O:16])=[O:15])=[C:12]([Cl:18])[CH:11]=[CH:10][C:8]=2[N:9]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27346381-(2-Methoxyethyl)piperazineHCID 234477912-Tert-butyl-6-chlorobenzoxazole-7-sulfonyl chloride

Product 1

HCID 68489961HCID 68489961, compound

Procedure

Followed the general procedure described in Example 1c, 2-tert-butyl-6-chloro-benzooxazole-7-sulfonyl chloride coupled with 2-methoxy-ethyl-piperazine to give the desired product 2a, 1.11 g (82%). LC-MS (m/z) 416.2 (M+H).

Sources & evidence

ORD record
ord-7745e89855824b9a94d943c600030072
Source dataset
uspto-grants-2010_05
Patent number
US07709485B2

Reaction notes

Loading…