HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 2-tert-Butyl-6-chloro-7-(4-methylpiperazine-1-sulfonyl)-benzooxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 2-Tert-butyl-6-chlorobenzoxazole-7-sulfonyl chloride | HCID 23447791 | — |
| Product | 2-tert-Butyl-6-chloro-7-(4-methylpiperazine-1-sulfonyl)-benzooxazole | HCID 23447836 | — |
Reaction Steps
Followed the general procedure described in Example 1c, 2-tert-butyl-6-chloro-benzooxazole-7-sulfonyl chloride coupled with methyl-piperazine to give the desired product 3a, 600 mg (53%). LC-MS (m/z) 372.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709485B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-9151384af6df4c4aad5b00e4c7ece23d |
| Source note | uspto-grants-2010_05 |