HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 58730618, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Fluorophenylboronic acid | HCID 2733986 | — |
| Reactant | HCID 58730617 | HCID 58730617 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 58730618 | HCID 58730618 | — |
Reaction Steps
Starting from 100 mg (0.18 mmol) of the bromide from Example 11A, reaction by general method [D] with 30.5 mg (0.22 mmol) of 3-fluorophenylboronic acid, 6.37 mg (0.01 mmol) of bis(triphenylphosphine)palladium(II) chloride and 23.07 mg (0.22 mmol) of sodium carbonate in 10 ml of 1,2-dimethoxyethane and 0.1 ml of water results in 22.6 mg (22% of theory) of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709491B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-3c17907fcd294e8c8e1e81fd699b4509 |
| Source note | uspto-grants-2010_05 |