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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233318Generated: November 1, 2026

Sodium Carbonate → HCID 58730618, compound

https://huagongshe.com/reaction/2233318

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant3-Fluorophenylboronic acidHCID 2733986—
ReactantHCID 58730617HCID 58730617—
CatalystHCID 178418476HCID 178418476—
SolventWaterHCID 962—
Solvent1,2-DimethoxyethaneHCID 8071—
ProductHCID 58730618HCID 58730618—

Reaction Steps

Starting from 100 mg (0.18 mmol) of the bromide from Example 11A, reaction by general method [D] with 30.5 mg (0.22 mmol) of 3-fluorophenylboronic acid, 6.37 mg (0.01 mmol) of bis(triphenylphosphine)palladium(II) chloride and 23.07 mg (0.22 mmol) of sodium carbonate in 10 ml of 1,2-dimethoxyethane and 0.1 ml of water results in 22.6 mg (22% of theory) of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709491B2
Source datasetuspto-grants-2010_05
ORD IDord-3c17907fcd294e8c8e1e81fd699b4509
Source noteuspto-grants-2010_05