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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233401Generated: October 30, 2026

3-Methanesulfonylbenzoic acid → N-{(2R)-3-[4-(3,4-Dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}-3-(methylsulfonyl)benzamide

https://huagongshe.com/reaction/2233401

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methanesulfonylbenzoic acidHCID 220380—
Reactant(2R)-1-amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl)propan-2-olHCID 11151315—
ProductN-{(2R)-3-[4-(3,4-Dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}-3-(methylsulfonyl)benzamideHCID 59295947—

Reaction Steps

Prepared as described in Example 1 from (2R)-1-amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]propan-2-ol (0.1 g) and 3-(methylsulfonyl)benzoic acid (0.063 g). Title compound obtained as white solid (0.017 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709500B2
Source datasetuspto-grants-2010_05
ORD IDord-9f151e9623ba4a51b6f39c0d0a25d9e6
Source noteuspto-grants-2010_05