HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Quinolinecarboxylic acid → N-{(2R)-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}quinoline-6-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Quinolinecarboxylic acid | HCID 82571 | — |
| Reactant | (2R)-1-amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl)propan-2-ol | HCID 11151315 | — |
| Product | N-{(2R)-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}quinoline-6-carboxamide | HCID 59296078 | — |
Reaction Steps
Prepared as described in Example from (2R)-1-amino-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]propan-2-ol (0.1 g) and quinoline-6-carboxylic acid (0.054 g). Title compound obtained as white solid (0.032 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709500B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-7c107d5c63fa4b02a633436e6ef8a296 |
| Source note | uspto-grants-2010_05 |