2486-69-3 → 4-Amino-N-{4-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-3-hydroxybutyl}-3-methoxybenzamide

HRID 2233411Notes

Reaction equation

HRID 2233411 reaction equation
[NH2:1][CH2:2][CH2:3][CH:4]([OH:21])[CH2:5][N:6]1[CH2:11][CH2:10][CH:9]([O:12][C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[C:15]([Cl:20])[CH:14]=2)[CH2:8][CH2:7]1.[NH2:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](O)=[O:28])=[CH:25][C:24]=1[O:32][CH3:33]>>[NH2:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([NH:1][CH2:2][CH2:3][CH:4]([OH:21])[CH2:5][N:6]2[CH2:7][CH2:8][CH:9]([O:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[C:15]([Cl:20])[CH:14]=3)[CH2:10][CH2:11]2)=[O:28])=[CH:25][C:24]=1[O:32][CH3:33]

Participants

3

Reactant 2

HCID 2880572486-69-3HCID 592960694-Amino-1-[4-(3,4-dichlorophenoxy)piperidin-1-yl]butan-2-ol

Product 1

HCID 592960684-Amino-N-{4-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-3-hydroxybutyl}-3-methoxybenzamide

Procedure

Prepared as described in Example 1 from 4-amino-1-[4-(3,4-dichlorophenoxy)piperidin-1-yl]butan-2-ol (0.26 g) and 4-amino-3-methoxybenzoic acid (0.130 g). Title compound obtained as white solid (0.080 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9dc4f6c7999d4801a12b2eb10f7bd1aa
Source dataset
uspto-grants-2010_05
Patent number
US07709500B2

Reaction notes

Loading…