Ethyl isonicotinate → HCID 60798512, compound

HRID 2233421Notes

Reaction equation

HRID 2233421 reaction equation
C(O[C:4](=[O:11])[C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1)C.[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH2:19][C:20]#[N:21]>>[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH2:19][C:4]([C:5]1[CH:6]=[CH:7][N:8]=[CH:9][CH:10]=1)=[O:11].[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH2:19][CH:20]([NH2:21])[C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 15291Ethyl isonicotinateHCID 67592Benzeneacetonitrile, 2-fluoro-

Product 2

HCID 60798512HCID 60798512, compoundHCID 60818444HCID 60818444, compound

Procedure

The title compound was generated from commercially available isonicotinic acid ethyl ester and (2-fluoro-phenyl)-acetonitrile according to the general procedure D described above. The intermediates 2-(2-fluoro-phenyl)-1-pyridin-4-yl-ethanone and 2-(2-fluoro-phenyl)-1-pyridin-4-yl-ethylamine were isolated and characterized.

Sources & evidence

ORD record
ord-fef24edaf6714dd3a29f0be4cb7c1db6
Source dataset
uspto-grants-2010_05
Patent number
US07709507B2

Reaction notes

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