Bromine → HCID 20146353, compound
Reaction equation
[CH3:1][C:2]1[N:3]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[CH2:14][CH2:15][C:16](=[O:19])[NH:17][N:18]=3)=[CH:9][CH:8]=2)[CH:4]=[CH:5][N:6]=1.BrBr>C(O)(=O)C>[CH3:1][C:2]1[N:3]([C:7]2[CH:8]=[CH:9][C:10]([C:13]3[CH:14]=[CH:15][C:16](=[O:19])[NH:17][N:18]=3)=[CH:11][CH:12]=2)[CH:4]=[CH:5][N:6]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Similarly, reaction of 4,5-dihydro-6-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone with bromine in acetic acid as described in this Example gives 6-[4-(2-methyl-1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone.
Sources & evidence
- ORD record
- ord-8aee20e16c1b4f2bb6128e7f4ff759b4
- Source dataset
- uspto-grants-1982_10
- Patent number
- US04353905
Reaction notes
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