HCID 18704056, compound → HCID 18704058, compound

HRID 2233541Notes

Reaction equation

HRID 2233541 reaction equation
[CH3:1][C:2]1[C:11]([N+:12]([O-])=O)=[CH:10][C:5]2=[N:6][C:7](=[O:9])[N:8]=[C:4]2[CH:3]=1>[Pd].C(O)C>[NH2:12][C:11]1[C:2]([CH3:1])=[CH:3][C:4]2=[N:8][C:7](=[O:9])[N:6]=[C:5]2[CH:10]=1

Participants

4

Reactant 1

HCID 18704056HCID 18704056, compound

Product 1

HCID 18704058HCID 18704058, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of (22) (0.25 g, 1.30 mmol) and 10% palladium on carbon (0.05 g) in ethanol (15 ml) was hydrogenated at atmospheric pressure for 4 h. The catalyst was filtered off through Celite, and the solvent was removed in vacuo to give (23) as a white solid.

Workup

  1. filtrationThe catalyst was filtered off through Celite
  2. customthe solvent was removed in vacuo

Sources & evidence

ORD record
ord-93c1c3720d6d4d078a47b9b834d02a0c
Source dataset
uspto-grants-2010_05
Patent number
US07709514B2

Reaction notes

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