HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 7,8,9,10-tetrahydro-3-methoxy-2-[3-(4-phenyl-1-piperidinyl)propoxy]-6H-dibenzo[b,d]pyran-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | Fumarate | HCID 5460307 | — |
| Reactant | 7,8,9,10-tetrahydro-2-[3-(methanesulfonyloxy)propoxy]-3-methoxy-6H-dibenzo[b,d]pyran-6-one | HCID 19927709 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 7,8,9,10-tetrahydro-3-methoxy-2-[3-(4-phenyl-1-piperidinyl)propoxy]-6H-dibenzo[b,d]pyran-6-one | HCID 19927665 | 100% |
Reaction Steps
Method B (20 h at 50° C.); starting materials: 7,8,9,10-tetrahydro-2-[3-(methanesulfonyloxy)propoxy]-3-methoxy-6H-dibenzo[b,d]pyran-6-one (example 80) and 4-phenylpiperidine; yield 100% (raw). Fumarate: method E; yield 72% on the basis of the methanesulfonyl compound; fusion point 184°-186° C. (from ethanol and acetone).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428038 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-8e588db9675443fbbb870f1f5253861a |
| Source note | uspto-grants-1995_06 |