Salicylaldehyde → HCID 136139912, compound

Participants

Reaction Conditions

Reaction Steps

570 g (5 moles) of 2,5-dimethyl-1,3,4-thiadiazole and 275 g (2.5 moles) of salicylaldehyde are mixed and slowly heated to 150° C., whilst passing nitrogen through the mixture. After having been kept at 150° C. for 30 hours, the mixture is cooled, excess 2,5-dimethyl-1,3,4-thiadiazole is distilled off and the residue is recrystallized from methylglycol. 304 g of yellow crystals (56% of theory), of melting point 253°-254° C. are obtained.

Provenance & Evidence