4-Hydrazinobenzonitrile → 4-[2-[1-Methyl-2-[4-(methylsulfonyl)phenoxy]ethylidene]hydrazino]-benzonitrile

HRID 2233758Notes

Reaction equation

HRID 2233758 reaction equation
[CH3:1][S:2]([C:5]1[CH:15]=[CH:14][C:8]([O:9][CH2:10][C:11](=O)[CH3:12])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[C:16]([C:18]1[CH:23]=[CH:22][C:21]([NH:24][NH2:25])=[CH:20][CH:19]=1)#[N:17]>>[CH3:12][C:11](=[N:25][NH:24][C:21]1[CH:22]=[CH:23][C:18]([C:16]#[N:17])=[CH:19][CH:20]=1)[CH2:10][O:9][C:8]1[CH:14]=[CH:15][C:5]([S:2]([CH3:1])(=[O:4])=[O:3])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 5837844-HydrazinobenzonitrileHCID 432349491-[4-(Methylsulfonyl)phenoxy]-2-propanone

Product 1

HCID 867611024-[2-[1-Methyl-2-[4-(methylsulfonyl)phenoxy]ethylidene]hydrazino]-benzonitrile

Procedure

The sub-title compound was prepared by the method of example 20 step (ii), using the product from example 20 step (i) (700 mg) and 4-cyanophenylhydrazine (400 mg). Yield 900 mg.

Sources & evidence

ORD record
ord-e12daffc46fd4c71b768ef99563b1fcb
Source dataset
uspto-grants-2010_05
Patent number
US07709521B2

Reaction notes

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