反应详情

温度

5 °C

In a 1-liter round-bottomed flask there were placed 200 ml methanol, 100 ml methylene chloride and 13.5 g (0.036 mole) of the perchlorate of step (c) above. The flask was cooled to about 5° C. and 5 g of sodium borohydrate were added in small quantities. The solution was then stirred for 2 hours at room temperature, concentrated, washed with water and extracted with methylene chloride. After drying and removing the solvent, there were obtained 8 g of yellow crystals, recrystallized from isopropyl ether, melted at 160° C. (yield 80%). The results of analysis are as follows:

1. customIn a 1-liter round-bottomed flask there were placed
2. concentrationconcentrated
3. washwashed with water
4. extractionextracted with methylene chloride
5. customAfter drying
6. customremoving the solvent