3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid → Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate

HRID 2233826Notes

Reaction equation

HRID 2233826 reaction equation
[CH3:1][O:2][C:3]([C:5]1[NH:6][C:7]([CH2:12]C)=[CH:8][C:9]=1[C:10]#[N:11])=[O:4].C(C1C=C(C)NC=1C(O)=O)#N>>[CH3:1][O:2][C:3]([C:5]1[NH:6][C:7]([CH3:12])=[CH:8][C:9]=1[C:10]#[N:11])=[O:4]

Participants

3

Reactant 2

HCID 450820233-cyano-5-methyl-1H-pyrrole-2-carboxylic acid2×HCID 685798823-Cyano-5-ethyl-1H-pyrrole-2-carboxylic acid methyl ester

Product 1

HCID 10797098Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate

Procedure

The title compound was prepared by a procedure analogous to Intermediate 27 starting from 3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid (Intermediate 32).

Sources & evidence

ORD record
ord-325596c9e8394d4d97cf24f8bd8beb52
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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