1H-Pyrrole-2-carboxylic acid, 5-methyl-, ethyl ester → 5-methyl-1H-pyrrole-2-carboxylic acid
Reaction equation
Br[C:2]1[CH:3]=[C:4]([C:8]([OH:10])=[O:9])[NH:5][C:6]=1[CH3:7].CC1NC(C(OCC)=O)=CC=1>>[CH3:7][C:6]1[NH:5][C:4]([C:8]([OH:10])=[O:9])=[CH:3][CH:2]=1Participants
3
Procedure
The title compound was synthesized by an analogous method to Intermediate 18 starting from ethyl 5-methyl-1H-pyrrole-2-carboxylate (Intermediate 20).
Sources & evidence
- ORD record
- ord-eafe0f038da94d828905b9724a1ab5cd
- Source dataset
- uspto-grants-2010_05
- Patent number
- US07709503B2
Reaction notes
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