HCID 68579996, compound → HCID 68579819, compound

HRID 2233852Notes

Reaction equation

HRID 2233852 reaction equation
Cl.[Cl:2]C1C(Cl)=C(C)NC=1C(NC1CCNCC1)=O.[Br:19][C:20]1[CH:21]=[C:22]([C:26]([NH:28][CH:29]2[CH2:34][CH2:33][N:32](C(OC(C)(C)C)=O)[CH2:31][CH2:30]2)=[O:27])[NH:23][C:24]=1[CH3:25]>>[ClH:2].[Br:19][C:20]1[CH:21]=[C:22]([C:26]([NH:28][CH:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)=[O:27])[NH:23][C:24]=1[CH3:25]

Participants

3

Reactant 2

HCID 68579996HCID 68579996, compoundHCID 68580239HCID 68580239, compound2×

Product 1

HCID 68579819HCID 68579819, compound

Procedure

Title compound was synthesized by an analogous method to Intermediate 1, starting from tert-butyl 4-{[(4-bromo-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidine-1-carboxylate (Intermediate 52).

Sources & evidence

ORD record
ord-325cc3c092f94fd281072de876a0cb01
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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