Ethyl 5-ethyl-1H-pyrrole-2-carboxylate → ethyl 3,4-dichloro-5-ethyl-1H-pyrrole-2-carboxylate

HRID 2233865Notes

Reaction equation

HRID 2233865 reaction equation
[CH2:1](C1NC(C(OCC)=O)=CC=1)C.[Cl:13][C:14]1[C:18]([Cl:19])=[C:17]([CH3:20])[NH:16][C:15]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22]>>[Cl:13][C:14]1[C:18]([Cl:19])=[C:17]([CH2:20][CH3:1])[NH:16][C:15]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22]

Participants

3

Reactant 2

HCID 597485Ethyl 5-ethyl-1H-pyrrole-2-carboxylate2×HCID 68519325Ethyl 3,4-dichloro-5-methyl-1H-pyrrole-2-carboxylate

Product 1

HCID 68579980ethyl 3,4-dichloro-5-ethyl-1H-pyrrole-2-carboxylate

Procedure

Title compound was synthesized from ethyl 5-ethyl-1H-pyrrole-2-carboxylate (Intermediate 12) by an analogous method to Intermediate 4.

Sources & evidence

ORD record
ord-4566bb28c32e4e96a8104a4f4d86a41c
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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