4-(N-Boc-amino)piperidine → HCID 86608263, compound

HRID 2233884Notes

Reaction equation

HRID 2233884 reaction equation
[N+](C1C([N:10]2[CH2:15][CH2:14][CH:13]([NH:16][C:17](=[O:23])[O:18][C:19]([CH3:22])([CH3:21])[CH3:20])[CH2:12][CH2:11]2)=NC=CC=1)([O-])=O.Cl[C:25]1[CH:30]=[C:29]([CH3:31])[N:28]=[C:27]([CH2:32][CH2:33][CH2:34][CH3:35])[N:26]=1.N1CCC(NC(=O)OC(C)(C)C)CC1>>[CH2:32]([C:27]1[N:26]=[C:25]([N:10]2[CH2:11][CH2:12][CH:13]([NH:16][C:17](=[O:23])[O:18][C:19]([CH3:21])([CH3:20])[CH3:22])[CH2:14][CH2:15]2)[CH:30]=[C:29]([CH3:31])[N:28]=1)[CH2:33][CH2:34][CH3:35]

Participants

4

Reactant 3

HCID 7238334-(N-Boc-amino)piperidineHCID 176064082-Butyl-4-chloro-6-methylpyrimidine2×HCID 44120582HCID 44120582, compound

Product 1

HCID 86608263HCID 86608263, compound

Procedure

Prepared in a manner analogous to Intermediate 38 starting from 4-chloro-2-butyl-6-methylpyrimidine (Intermediate 97) and tert-butyl piperidin-4-ylcarbamate.

Sources & evidence

ORD record
ord-bf452f7e2eae4152864fcc7f509f2225
Source dataset
uspto-grants-2010_05
Patent number
US07709503B2

Reaction notes

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