HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-chloro-5-ethyl-1H-pyrrole-2-carboxylic acid → 2-Chloro-6-(4-{[(4-chloro-5-ethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-chloro-5-ethyl-1H-pyrrole-2-carboxylic acid | HCID 68579825 | — |
| Reactant | 2-(4-Aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride | HCID 86608255 | — |
| Product | 2-Chloro-6-(4-{[(4-chloro-5-ethyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinamide | HCID 86608272 | — |
Reaction Steps
Title compound was synthesized by an analogous method to Example 18 by coupling 2-(4-aminopiperidin-1-yl)-6-chloroisonicotinamide hydrochloride (Intermediate 70) with 4-chloro-5-ethyl-1H-pyrrole-2-carboxylic acid (Intermediate 71).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-d5098d051b6f4e59b6d53dd6bc3c8439 |
| Source note | uspto-grants-2010_05 |