HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromothiazole → 4-bromo-5-methyl-N-[1-(1,3-thiazol-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromothiazole | HCID 76430 | — |
| Reactant | HCID 68579819 | HCID 68579819 | — |
| Product | 4-bromo-5-methyl-N-[1-(1,3-thiazol-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide | HCID 68581128 | — |
Reaction Steps
Title compound was synthesized by an analogous method to Example 123 by coupling 4-bromo-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 57) with 2-bromo-1,3-thiazole (commercially available).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-c7116f2897bc4e5fa97215acbd4f1e88 |
| Source note | uspto-grants-2010_05 |