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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2233968Generated: October 30, 2026

5-Bromo-1-methyl-1H-tetrazole → 4-Bromo-5-methyl-N-[1-(1-methyl-1H-tetrazol-5-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide

https://huagongshe.com/reaction/2233968

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-1-methyl-1H-tetrazoleHCID 12797446—
ReactantHCID 68579819HCID 68579819—
Product4-Bromo-5-methyl-N-[1-(1-methyl-1H-tetrazol-5-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamideHCID 68582566—

Reaction Steps

Title compound was synthesized by an analogous method to Example 123 by coupling 4-bromo-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 57) with 5-bromo-1-methyl-1H-tetrazole (Can. J. Chem. 1971, 49, 2139).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709503B2
Source datasetuspto-grants-2010_05
ORD IDord-61fc3059c4704b14a36ba378eea08da2
Source noteuspto-grants-2010_05