HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dichloro-N-[1-(5-cyano-4-hydroxy-1,3-thiazol-2-yl)piperidin-4-yl]-5-methyl-1H-pyrrole-2-carboxamide → HCID 68579602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dichloro-N-[1-(5-cyano-4-hydroxy-1,3-thiazol-2-yl)piperidin-4-yl]-5-methyl-1H-pyrrole-2-carboxamide | HCID 68579854 | — |
| Reactant | HCID 68580031 | HCID 68580031 | — |
| Product | HCID 68579602 | HCID 68579602 | — |
Reaction Steps
The title compound was synthesized by an analogous method to Example 42 by coupling methyl 5-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-1,3,4-oxadiazole-2-carboxylate (Intermediate 160) with 3,4-dichloro-5-methyl-1H-pyrrole-2-carboxylic acid (Intermediate 3). De-BOC and coupling should be separate steps.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709503B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-2686b8a905c64384b663c0c035e8fc0d |
| Source note | uspto-grants-2010_05 |