HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234108Generated: November 1, 2026
Phenylboronic Acid → HCID 68638614, compound
https://huagongshe.com/reaction/2234108
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenylboronic Acid | HCID 66827 | — |
| Reactant | HCID 68636107 | HCID 68636107 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 68638614 | HCID 68638614 | 100.7% |
Reaction Steps
68 mg 3-Iodo-2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-6-piperidin-1-ylmethyl-1H-indole, 17 mg phenylboronic acid, 86 mg potassium phosphate tribasic n-hydrate, and 12 mg tetrakis(triphenylphosphine)palladium(0) are dissolved in a mixture of 2.0 mL toluene and 72 μL water. Argon is bubbled through the solution for 5 minutes. The mixture is heated to 90° C. for 2.5 hours. Concentration in vacuo affords 62 mg crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07709466B2 |
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| Source dataset | uspto-grants-2010_05 |
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| ORD ID | ord-b8bb718c5bd64ada862bcdf5c868a2eb |
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| Source note | uspto-grants-2010_05 |
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