Triethylamine → HCID 86738592, compound

Participants

Reaction Steps

Cyclopropylcarboxylic acid chloride (6.60 g., 6.32 mmol) is added dropwise to a solution of 3-hydrazino-1-methyl-6-methoxy-1H-quinoxalin-2-one (52.6 mmol) and triethylamine (6.38 g., 63.2 mmol) in 500 ml. of dioxane and the mixture stirred at room temperature for 20 hours. The dioxane is then removed under vacuum and the residue washed with water, filtered, and dried under vacuum to give a crude yield of 12.8 g. (95%). A 4.8 g. sample of this material is recrystallized from 100 ml. of acetonitrile to obtain purified product.

Provenance & Evidence