Loxoprofen → Calcium Stearate

Participants

Reaction Steps

A lubricant composition was formed by first adding 40.00 gms of oxidized CS-600 low viscosity byproduct wax (viscosity: 11 cps; acid number: 14.7 mg KOH/gram; Mettler drop point: 109.5° C.), 29.46 gms of hydrocarbon wax and 98.30 gms of stearic acid to a reactor vessel. The combination was melted and held at 140° C. with slight agitation. Approximately 6.00 gms of calcium hydroxide was then added with agitation. The calcium hydroxide reacted with the stearic acid, forming a calcium stearate product and water as a byproduct. The high temperatures converted the water to steam, generating foam. Approximately 20.24 gms of glycerol monostearate was then added to dissipate the foam. Next, another 6.00 gms of calcium hydroxide was added to the vessel with agitation. The mixture was mixed until water formation stopped, and it was slowly stirred to remove any entrapped air. The mixture was then held for a finishing step such as prilling or pastiliating. The resulting lubricant composition contained 20.65% of an oxidized, low viscosity byproduct wax, 15.21% of a hydrocarbon wax, 6.91% residual stearic acid, 10.45% residual glycerol monostearate, and 46.77% calcium stearate. At 140° C., this lubricant composition had a viscosity of 300 centipoise and an acid number of 15.1 mg KOH/gram.

Provenance & Evidence