Loxoprofen → Calcium Stearate

Participants

Reaction Steps

A lubricant composition was formed by first adding 43.00 gms of oxidized CS-600 low viscosity byproduct wax (viscosity: 11 cps; acid number: 14.7 mg KOH/gram; Mettler drop point: 109.5° C.), 122.50 gms of stearic acid, 15.5 gms of calcium hydroxide and 19.0 gms of glycerol monostearate to a reactor vessel. The combination was melted and held at 140° C. with slight agitation. The calcium hydroxide reacted with the stearic acid, forming a calcium stearate product and water as a byproduct. The high temperatures converted the water to steam, generating foam, and the foam was dissipated by the glycerol monostearate. The mixture was mixed until water formation stopped, and it was slowly stirred to remove any entrapped air. The mixture was then held for a finishing step such as prilling or pastillating. The resulting lubricant composition contained 22.42% of the oxidized byproduct wax, 6.68% residual stearic acid, 9.90% residual glycerol monostearate, and 61.00% calcium stearate. This lubricant composition had an acid number of 23.2 mg KOH/gram and a viscosity of 1900 centipoise at 140° C.

Provenance & Evidence