Acetic Anhydride → HCID 19834543, compound

HRID 223418Notes

Reaction equation

HRID 223418 reaction equation
[NH:1]([C:8]1[C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11]([CH3:17])[NH:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18](OC(=O)C)(=[O:20])[CH3:19]>>[C:18]([N:10]1[C:11]([CH3:17])=[C:12]([C:13]([O:15][CH3:16])=[O:14])[C:8]([NH:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[N:9]1)(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 19834564HCID 19834564, compound

Product 1

HCID 19834543HCID 19834543, compound

Procedure

23 g of 3-anilino-4-methoxycarbonyl-5-methylpyrazole is dissolved in 51 g of acetic anhydride and brought to the boil. After 15 minutes' boiling the mixture is allowed to cool, poured into ice water and stirred for 30 minutes. The solid which separates is isolated and recrystallized from methanol; m.p. 115°-116° C.

Workup

  1. temperatureto cool
  2. customThe solid which separates is isolated
  3. customrecrystallized from methanol

Sources & evidence

ORD record
ord-d51e65e466cd44f8a05bac1a05832ea3
Source dataset
uspto-grants-1982_10
Patent number
US04354031

Reaction notes

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