4-amino-N-(3-dimethylamino-2,2-dimethyl-propyl)-3-methoxy-benzamide → N-(3-dimethylamino-2,2-dimethyl-propyl)-4-[(2-methyl-3-oxo-6-propan-2-yl-2,6,8,10-tetrazabicyclo[5.4.0]undeca-7,9,11-trien-9-yl)amino]benzamide
Reaction equation
Cl[C:2]1[N:12]=[C:11]2[C:5]([N:6]([CH3:17])[C:7](=[O:16])[CH2:8][CH2:9][N:10]2[CH:13]([CH3:15])[CH3:14])=[CH:4][N:3]=1.[NH2:18][C:19]1[CH:35]=[CH:34][C:22]([C:23]([NH:25][CH2:26][C:27]([CH3:33])([CH3:32])[CH2:28][N:29]([CH3:31])[CH3:30])=[O:24])=[CH:21][C:20]=1OC>>[CH3:31][N:29]([CH3:30])[CH2:28][C:27]([CH3:32])([CH3:33])[CH2:26][NH:25][C:23](=[O:24])[C:22]1[CH:21]=[CH:20][C:19]([NH:18][C:2]2[N:12]=[C:11]3[C:5](=[CH:4][N:3]=2)[N:6]([CH3:17])[C:7](=[O:16])[CH2:8][CH2:9][N:10]3[CH:13]([CH3:15])[CH3:14])=[CH:35][CH:34]=1Participants
3
Reactant 2
Product 1
Procedure
Prepared from Intermediate 76 and Intermediate 22.
Sources & evidence
- ORD record
- ord-409ca5620a774e5485f9141dbd7f4a32
- Source dataset
- uspto-grants-2010_05
- Patent number
- US07709471B2
Reaction notes
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