4-amino-3-methoxy-N-(1-methylpyrrolidin-3-yl)benzamide → HCID 68683424, compound

HRID 2234462Notes

Reaction equation

HRID 2234462 reaction equation
NC1C=CC(C(NC2CCN(C)C2)=O)=CC=1OC.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:34]=[CH:35][C:36]=1[N+:37]([O-])=O)[C:24]([NH:26][CH2:27][CH2:28][N:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1)=[O:25]>>[NH2:37][C:36]1[CH:35]=[CH:34][C:23]([C:24]([NH:26][CH2:27][CH2:28][N:29]2[CH2:33][CH2:32][CH2:31][CH2:30]2)=[O:25])=[CH:22][C:21]=1[O:20][CH3:19]

Participants

3

Reactant 2

HCID 686841234-amino-3-methoxy-N-(1-methylpyrrolidin-3-yl)benzamideHCID 686860143-methoxy-4-nitro-N-(2-pyrrolidin-1-ylethyl)benzamide2×

Product 1

HCID 68683424HCID 68683424, compound

Procedure

The title compound was prepared in quantitative yield by an analogous method to the preparation of Intermediate 187, on a 2 g scale utilising 3-methoxy-4-nitro-N-(2-pyrrolidin-1-ylethyl)benzamide (Intermediate 193).

Sources & evidence

ORD record
ord-9a6eb6f912124e238c5b484ace202ec0
Source dataset
uspto-grants-2010_05
Patent number
US07709471B2

Reaction notes

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