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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234482Generated: October 31, 2026

1-Pyrrolidineethanamine → 4-amino-3-chloro-N-(2-pyrrolidin-1-ylethyl)benzamide

https://huagongshe.com/reaction/2234482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PyrrolidineethanamineHCID 1344—
Reactant4-amino-3-chloro-N-(1-ethyl-4-piperidyl)benzamideHCID 64321494—
Product4-amino-3-chloro-N-(2-pyrrolidin-1-ylethyl)benzamideHCID 59763672—

Reaction Steps

The title compound was prepared by an analogous method to the preparation of Intermediate 212, on a 15 mmol scale utilising 2-pyrrolidin-1-ylethanamine (Aldrich; 1.885 g, 16.5 mmol), as a tan coloured solid (2.67 g, 66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709471B2
Source datasetuspto-grants-2010_05
ORD IDord-6a0cd9ab1fd14a109e9d119a3adeefc2
Source noteuspto-grants-2010_05