HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethylpiperidin-4-amine → 4-amino-N-(1-ethyl-4-piperidyl)-2,5-difluoro-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethylpiperidin-4-amine | HCID 3734990 | — |
| Reactant | 4-amino-2,5-difluoro-N-[(3R)-1-methylpyrrolidin-3-yl]benzamide | HCID 68682472 | — |
| Product | 4-amino-N-(1-ethyl-4-piperidyl)-2,5-difluoro-benzamide | HCID 68684847 | — |
Reaction Steps
The title compound was prepared by an analogous method to the preparation of Intermediate 229, on a 5.77 mmol scale utilising 4-amino-1-ethylpiperidine (Fluorochem; 815 mg, 6.35 mmol), as an orange solid (1.23 g, 75%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709471B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-190563b857ff4a66a5fda50e9e900829 |
| Source note | uspto-grants-2010_05 |