HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 57731620, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68694688 | HCID 68694688 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57731620 | HCID 57731620 | — |
Reaction Steps
To a solution of 2-tert-Butoxycarbonylamino-5-[3-(1H-indol-7-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-benzoic acid (308 mg, 0.66 mmol) in dichloromethane (9 mL) was added trifluoroacetic acid. The resulting solution was stirred for 2 hours at room temperature. The solution was concentrated to give the crude 2-amino-5-[3-(1H-indol-7-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-benzoic acid which was used in next step without further purification. MS: m/z 369 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709645B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-e5f76d4646ff4eef93d174caf9f7f88e |
| Source note | uspto-grants-2010_05 |