Trifluoroacetic acid methylene chloride → HCID 68691136, compound

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2-Amino-5-[3-(2-methoxy-phenyl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-benzoic acid tert-butyl ester (1.13 g, 1.98 mmol) was treated with 10 mL of dichloromethane/trifluoracetic acid (1:1) for 24 h. The solution was dried in vacuo to afford 2-amino-5-[3-(2-methoxy-phenyl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-benzoic acid trifluoroacetate (quantitative). MS: m/z 514 (M+H+).

Provenance & Evidence