Potassium Cyanide → HCID 68582824, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2,7-dibromo-9,9-dipropyl-3-methoxyfluorene (83 g, 0.19 mol), and copper(I) cyanide (50 g, 0.56 mol) in anhydrous dimethylformamide (70.0 mL) was stirred under reflux and argon for 18 hours. The reaction was allowed to cool to 90° C. and treated with a solution of potassium cyanide (100 g) in water (350 mL). The resulting mixture was stirred rapidly for a further 4.5 hours. The granular product was collected by filtration, crushed, washed with water and dried. The tan colored solid was extracted from a soxhlet with methylcyclohexane. Cooling and seeding of the methylcyclohexane extract afforded 2,7-dicyano-9,9-dipropyl-3-methoxyfluorene upon filtration (62.6 g; yield 99%).

Provenance & Evidence