Benzophenone imine → 4-[cis-3,5-Dimethyl-1-piperazinyl]-N-(diphenylmethylidene)-2-pyridinamine

HRID 2234985Notes

Reaction equation

HRID 2234985 reaction equation
Cl[C:2]1[CH:7]=[C:6]([N:8]2[CH2:13][C@H:12]([CH3:14])[NH:11][C@H:10]([CH3:15])[CH2:9]2)[CH:5]=[CH:4][N:3]=1.[C:16](=[NH:29])([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:15][C@H:10]1[NH:11][C@@H:12]([CH3:14])[CH2:13][N:8]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([N:29]=[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:7]=2)[CH2:9]1

Participants

3

Reactant 2

HCID 136809Benzophenone imineHCID 58988144cis-1-(2-Chloro-4-pyridinyl)-3,5-dimethylpiperazine2×

Product 1

HCID 589881374-[cis-3,5-Dimethyl-1-piperazinyl]-N-(diphenylmethylidene)-2-pyridinamine

Procedure

The title compound was prepared in a similar manner to cis-1-(2-chloro-4-pyridinyl)-3,5-dimethylpiperazine (D19) using cis-1-(2-chloro-4-pyridinyl)-3,5-dimethylpiperazine (D19) and benzophenone imine as the starting materials. MS (ES+) m/e 371 [M+H]+.

Sources & evidence

ORD record
ord-e99b69ccc98c4a1c8377c592cddecbe7
Source dataset
uspto-grants-2010_05
Patent number
US07713978B2

Reaction notes

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