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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234993Generated: October 30, 2026

N-{5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinyl}-2,2,2-trifluoroacetamide → 5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinamine

https://huagongshe.com/reaction/2234993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-{5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinyl}-2,2,2-trifluoroacetamideHCID 58988131—
Reactant5-[cis-3,5-Dimethyl-4-(phenylmethyl)-1-piperazinyl]-2-(methyloxy)-3-pyridinamineHCID 58988135—
Product5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinamineHCID 58988152—

Reaction Steps

The title compound was prepared in a manner similar to 5-[cis-3,5-dimethyl-4-(phenylmethyl)-1-piperazinyl]-2-(methyloxy)-3-pyridinamine (D29) using N-{5-[cis-3,5-dimethyl-1-piperazinyl]-3-pyridinyl}-2,2,2-trifluoroacetamide (D35) as the starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713978B2
Source datasetuspto-grants-2010_05
ORD IDord-c1c66408b80d4188af524663a761addf
Source noteuspto-grants-2010_05