HCID 70882505, compound → HCID 68683061, compound

Participants

Reaction Steps

1,1-Dimethylethyl (2R,6S)-4-[6-({[2-chloro-4-(5-methyl-2-thienyl)phenyl]sulfonyl}amino)-5-(methyloxy)-2-pyridinyl]-2,6-dimethyl-1-piperazinecarboxylate (D16) (0.170 g) was dissolved in 4N HCl/dioxane (5 mL) added and the reaction stirred at rt for 24 hours. The reaction mixture was evaporated and triturated with ethyl acetate/ether ×3 to give a white solid which was dried at 50° C. under high vac to give the compound as a white solid (E8)(0.066 g). MS (ES+) m/e 507/509 [M+H]+.

Provenance & Evidence