Sulfuric Acid → HCID 178525761, compound

Participants

Reaction Steps

70 mg (0.17 mmol) of ethyl trans-4-(4,5-diphenylpyrimidin-2-ylamino)-cyclohexanecarboxylate were mixed with 872 μl of tetrahydrofuran and 872 μl of 1N aqueous lithium hydroxide solution and stirred at room temperature for 48 hours. The reaction mixture was diluted with water and acidified with sulfuric acid, and the resulting precipitate was filtered off with suction. 64 mg (98%) of the desired product were obtained.

Provenance & Evidence