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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2235121Generated: October 30, 2026

3-(Trifluoromethoxy)benzene-1-sulfonyl chloride → HCID 68695580, compound

https://huagongshe.com/reaction/2235121

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethoxy)benzene-1-sulfonyl chlorideHCID 2777218—
ReactantHCID 16051866HCID 16051866—
ProductHCID 68695580HCID 68695580—

Reaction Steps

4-{[1-(3-Trifluoromethoxy-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-benzoic acid, MS (ISP): m/e=505.1 (M−H), was prepared in analogy to example 30, steps 1 to 6. Step 5 was performed using 3-trifluoromethoxy-benzenesulfonyl chloride, yielding 4-{[1-(3-trifluoromethoxy-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-benzoic acid ethyl ester, which was hydrolyzed in step 6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713996B2
Source datasetuspto-grants-2010_05
ORD IDord-67bd1b30ff384fa38b69ec4673156127
Source noteuspto-grants-2010_05