5-Chloro-2-methoxybenzene-1-sulfonyl chloride → HCID 68695985, compound

HRID 2235165Notes

Reaction equation

HRID 2235165 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([CH2:9][CH2:10][NH:11]2)=[C:7]([CH3:14])[CH:6]=1)=[O:4].[Cl:15][C:16]1[CH:17]=[CH:18][C:19]([O:26][CH3:27])=[C:20]([S:22](Cl)(=[O:24])=[O:23])[CH:21]=1>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([CH2:9][CH2:10][N:11]2[S:22]([C:20]2[CH:21]=[C:16]([Cl:15])[CH:17]=[CH:18][C:19]=2[O:26][CH3:27])(=[O:23])=[O:24])=[C:7]([CH3:14])[CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 27342725-Chloro-2-methoxybenzene-1-sulfonyl chlorideHCID 68694348Methyl 2,3-dihydro-4-methyl-1H-indole-6-carboxylate

Product 1

HCID 68695985HCID 68695985, compound

Procedure

4-Methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester was reacted with 5-chloro-2-methoxybenzenesulfonyl chloride in analogy to example 34, step 2, yielding 1-(5-chloro-2-methoxy-benzenesulfonyl)-4-methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester. Pink solid, MS (ISP): m/e 396.1 (M+H).

Sources & evidence

ORD record
ord-cba2c28ca3dd41468ee593d7c54188e1
Source dataset
uspto-grants-2010_05
Patent number
US07713996B2

Reaction notes

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