HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-methoxybenzene-1-sulfonyl chloride → 1-(5-chloro-2-methoxy-benzenesulfonyl)-3-methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-methoxybenzene-1-sulfonyl chloride | HCID 2734272 | — |
| Reactant | 3-Methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester | HCID 68696351 | — |
| Product | 1-(5-chloro-2-methoxy-benzenesulfonyl)-3-methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester | HCID 68696198 | — |
Reaction Steps
3-Methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester was reacted with 5-chloro-2-methoxybenzenesulfonyl chloride in analogy to example 34, step 2, yielding 1-(5-chloro-2-methoxy-benzenesulfonyl)-3-methyl-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester. Off-white solid, MS (ISP): m/e 395.9 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713996B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-d48e3f5768d7443389d6f01be31c9916 |
| Source note | uspto-grants-2010_05 |