反应详情

Using the method of Example 167, 4-oxo-4-(2-oxo-oxazolidin-3-yl)-butyraldehyde (Dominique Urban, Troels Skrydstrup, and Jean-Marie Beau, J. Org. Chem., 1998, 63(8), 2507-2516) (4.2 g, 24.54 mmol) and (cis-4-amino-cyclohexyl)-methanol (Thomas P. Johnston, etc. J. Med. Chem., 1977, 20(2), 279-290) (3.17 g, 24.54 mmol) yield 4.87 g (100%) of the title compound as a colorless oil.