HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxyphenylboronic acid → HCID 59299430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxyphenylboronic acid | HCID 2734360 | — |
| Reactant | HCID 59299482 | HCID 59299482 | — |
| Product | HCID 59299430 | HCID 59299430 | 72% |
Reaction Steps
Using the procedure to synthesize Example 81 and using reagents 1-adamantan-2-yl-3-(4-bromo-2-chloro-benzyl)-pyrrolidin-2-one (Example 76) (1.0 g, 2.4 mmol) and 4-hydroxyphenylboronic acid (980 mg, 7.1 mmol) affords 740 mg (72%) of the title compound: Mass spectrum (apci) m/z=436.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713979B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-81fc1a27d8274dab9aa3b00fdc188e6c |
| Source note | uspto-grants-2010_05 |