N-bromobutanimide → HCID 59299492, compound

Participants

Reaction Steps

Place 3-(2,6-dichloro-3-hydroxybenzyl)-1-cyclohexylpyrrolidin-2-one (1.116 g, 3.26 mmol) in acetic acid (5 mL). Add NBS (0.609 g, 3.42 mmol) and stir at room temperature for 2 hours. Pour reaction mixture onto water, filter, and dry to give 1.165 g (85%) of the title compound. Mass spectrum (apci) m/z=422.1 (M+H).

Provenance & Evidence