Hydrochloric Acid → HCID 59300828, compound

Participants

Reaction Steps

(rac)-N-(3-Isopropyl-1-methyl-6-nitro-2-oxo-2,3-dihydro-1H-indol-5-yl)-acetamide (686 mg) is dissolved in 2-propanol (4 ml) and hydrochloric acid (6 N; 6 ml) and heated for 1 h at 100° C. After a typical aqueous work-up the crude material is purified by flash chromatography on silica gel eluting with light petroleum/EtOAc (1:1) to give the title compound (429 mg).

Provenance & Evidence